Scientists investigating the cellular basis for itching have made an important discovery, and one that could lead to new treatments of chronic conditions like eczema. The breakthrough centers on what’s known as mechanical itching, with the research team behind it demonstrating how a protein can be blocked to alleviate itching sensation in mouse models of the condition.Much of the itching that we experience as humans is driven by activation of the histamine system. This system releases histamine as part of the body’s reaction to things like mosquito bites, pollen or certain medications, and creates the type of itchiness and redness we often see as a result of those triggers.
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